Practical recommendations for the application of DE 59/2013

The changes introduced with Council Directive 2013/59/Euratom will require European Member States adapt their regulations, procedures and equipment to the new high standards of radiation safety. These new requirements will have an impact, in particular, on the radiology community (including medical physics experts) and on industry. Relevant changes include new definitions, a new dose limit for the eye lens, non-medical imaging exposures, procedures in asymptomatic individuals, the use and regular review of diagnostic reference levels (including interventional procedures), dosimetric information in imaging systems and its transfer to the examination report, new requirements on responsibilities, the registry and analysis of accidental or unintended exposure and population dose evaluation (based on age and gender distribution). Furthermore, the Directive emphasises the need for justification of medical exposure (including asymptomatic individuals), introduces requirements concerning patient information and strengthens those for recording and reporting doses from radiological procedures, the use of diagnostic reference levels, the availability of dose-indicating devices and the improved role and support of the medical physics experts in imaging

EP-1526: Analysis of dose deposition in lung lesions: a modified PTV for a more robust optimization

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Equilibri di Nash in giochi a due persone simmetrici a somma zero

In questa tesi vengono studiate alcune proprietà dei giochi a due giocatori, finiti, simmetrici e a somma zero, con particolare enfasi sulle caratteristiche geometriche dell'insieme degli equilibri di Nash. Vengono analizzati, inoltre, il gioco Sasso-Carta-Forbice e le sue generalizzazioni

Heat transfer and pressure drop during condensation of the low GWP refrigerant R1234yf

The present paper reports local heat transfer coefficients measured during condensation of R1234yf within a single circular 0.96 mm diameter minichannel and compares them to the ones of R134a. This experimental work is carried out in a unique test apparatus which allows to determine the local heat flux extracted from the condensing fluid from the temperature profile of the coolant. For this purpose, the temperatures of the coolant and of the wall are measured along the test section. The saturation temperature is determined from the saturation pressure which is measured at inlet and outlet of the test channel. Condensation tests are carried out at mass fluxes ranging between 200 and 1000 kg m2 s1 and the heat transfer coefficients result to be lower as compared to the ones of R134a. Since the saturation temperature drop directly affects the heat transfer rate, the pressure drop during adiabatic two-phase flow of R1234yf is also measured and compared to R134a

Flow boiling of R1234yf in a 1 mm diameter channel

Since many HFC refrigerants have relatively large values of GWP, recent development efforts have been initiated to investigate halogenated olefins as possible refrigerants, with fluorinated propene isomers, in particular, having emerged as possible solutions. Specifically, R1234yf has emerged as an R134a replacement for automotive applications. In this paper, the local heat transfer coefficient measured during flow boiling of R1234yf in a 1mm diameter circular microchannel is reported and compared to R134a. During tests, the heat is provided to the boiling fluid by using a secondary fluid. Therefore the heat flux is not imposed but instead it is the result of the inlet temperatures of the two fluids and the thermal resistances on the two sides, as it occurs in actual heat exchangers for automotive and air-conditioning applications. Flow boiling tests are carried out at 31\ub0C saturation temperature and mass fluxes ranging between 200 kg m-2 s-1 and 600 kg m-2 s-1

Involvement of energetic metabolism in the effects of ischemic postconditioning on the ischemic-reperfused heart of fed and fasted rats

The effects of ischemic-postconditioning (IPOC) on functional recovery and cell viability of ischemic-reperfused hearts from fed and fasted rats were studied in relation to triacylglycerol and glycogen mobilization, ATP content, glucose-6-phosphate dehydrogenase activity and reduced/oxidized glutathione (GSH/GSSG). Oxidative damage was estimated by measuring thiobarbituric acid reactive substances (TBARS). IPOC improved contractile recovery and cell viability in the fed but attenuated them in the fasted hearts. In both groups ischemia lowered glycogen. IPOC further reduced it. Triacylglycerol remained unchanged during ischemia-reperfusion in both groups, but triacylglycerol mobilization was activated by IPOC in the fasted group. ATP was increased by IPOC in the fed hearts, but lowered in the fasted ones, which appeared to be associated with the rates of ATP synthesis in isolated mitochondria. In the fed hearts IPOC raised glucose-6-phosphate dehydrogenase activity and GSH/GSSG, and lowered TBARS. These results suggest that IPOC effects are associated with changes in the ATP supply, mobilization of energy sources and glutathione antioxidant ratio. © 2011 The Physiological Society of Japan and Springer.Fil: Marina Prendes, María Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiología Humana; ArgentinaFil: Hermann, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiología Humana; ArgentinaFil: Torresin, María Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiología Humana; ArgentinaFil: Souto, P.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiopatología; ArgentinaFil: Tallis, Silvina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiopatología; ArgentinaFil: Savino, Enrique Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiología Humana; ArgentinaFil: Varela, Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Ciencias Biológicas. Cátedra de Fisiología Humana; Argentin